Custom Synthesis

Custom synthesis means the exclusive synthesis of compounds on behalf of the customer — you can order a specific molecule that is only synthesized on your request on the scale, with the purity and with the specification or methods you require.

Custom Synthesis is Optimal for Synthesizing

Capabilities

  • Gram to multi kg quantities
  • Particular expertise in synthesis of homogenous catalysts, ligands, and reagents/building blocks as well as polymer chemistry and material science
  • Customized packaging and customized specification

Made-to-Order

Some of Our Custom Synthesis Reactions

Photo Chlorination

It is a chlorination reaction that is initiated by light. Usually a C-H bond is converted to a C-Cl bond. Photochlorination is carried out on an industrial scale. The process is exothermic and proceeds as a chain reaction initiated by the homolytic cleavage of molecular chlorine into chlorine radicals by ultraviolet radiation.

Vilsmeier Haack Reaction

Vilsmeier reagent is the active intermediate in the formylation reactions. The Vilsmeier reaction or Vilsmeier-Haack reaction uses mixtures of dimethylformamide and phosphorus oxychloride to generate the Vilsmeier reagent, which in turn attacks a nucleophilic substrate and eventually hydrolyzes to give formyl.

Synthesis of Acylisocyanates

In organic chemistry, isocyanate is the functional group with the formula R-N=C=O. Organic compounds that contain an isocyanate group are referred to as isocyanates. An organic compound with two isocyanate groups is known as a diisocyanate. Diisocyanates are manufactured for the production of polyurethanes, a class of polymers.

Grignard Reaction

The Grignard reaction is a prominent textbook process to form carbon-carbon bonds. In this reaction, the so-called Grignard reagent, an organomagnesium species RMgX where R is an organic residue and X is a halogen (usually Cl or Br), promotes the addition of its organic residue to an electrophilic substrate.

Esterification

Esterification is the process of combining an organic acid (RCOOH) with an alcohol (ROH) to form an ester (RCOOR) and water; or a chemical reaction resulting in the formation of at least one ester product. Ester is obtained by an esterification reaction of an alcohol and a carboxylic acid. Some esters can be prepared by esterification where a carboxylic acid and an alcohol, heated in the presence of a mineral acid catalyst, form an ester and water. The reaction is reversible.

N-Methylation

N-Methylation is a significant chemical transformation used extensively in pharmaceutical and agrochemical synthesis to introduce methyl groups onto nitrogen atoms, modifying the biological activity and physical properties of compounds.

Thiation of Carbonyl Moiety

The thiocarbonyl group is widely found in a great variety of organic compounds. Thio analogues of ketones, lactones, amides, and esters are very important biological molecules, and they are widely used in medicine as therapeutic agents with a wide range of biological activities. Thiocarbonyl compounds have also been widely used in organic synthesis as precursors of organosulfur compounds.

Wolff-Kishner Reduction

Wolff-Kishner reduction mechanism begins with the formation of a hydrazone anion which then releases the nitrogen molecule to form a carbanion. This carbanion then reacts with water in the system to give a hydrocarbon. This reduction is an organic reaction where aldehydes and ketones are reduced to alkanes.